Amazing advances in microbiology over the past 20 years forced us to think in terms of ever shifting boundaries between the known and the unknown about microorganisms. Just as the first microscopes unveiled an unseen microbial world, the use of modern techniques to enumerate different kinds and numbers of single-cell organisms has forever changed perceptions of the living world. Today we are a witness to a revolutionary innovation in microbial world where scientists have created the world's first synthetic life form in a landmark experiment that paves the way for designer organisms that are built rather than evolved. Though innovation is rapidly becoming a key strategic driver for every system as we enter the second decade of the 21st century, most of us seem to struggle with the understanding on what it is and how to move forward on our journey into innovation. Being able to look at the current trends and see where they will take us is an interesting and thought provoking exercise. Let’s meet with all our past experience and current knowledge to find out the future trends of Microbiology during the 53rd Annual Conference of AMI with a theme ‘Microbial world: Recent Innovations and Future Trends’.